Alli -- manufactured by GlaxoSmithKline
-- is a less potent form of the prescription drug
orlistat. The drug orlistat was marketed under
the trade name Xenical by
Roche Holding, which had limited success on the market.
But, GlaxoSmithKline's expectations for Alli
are much higher than those for Xenical.
The company is spending millions marketing the drug on television,
radio and print ads and expects to net at least $1.5 billion
in annual sales.
Since hitting the market in June, Alli's been going strong
and the exciting media hype has also created strong interest
among consumers. But people should know that alli
diet pill is a program; it is not a magic pill.
"Studies have shown that those who combined the use
of Alli with diet and exercise only lost about three
pounds more than people who only dieted and exercised.
Brandi Reed--pharmacist at Target's I-55 North store in
Jackson—said,”Alli works by blocking
enzymes that digest fat, which prevents the body
from absorbing about one-fourth of the amount of fat that
is eaten. The undigested fat is then excreted from the body,
creating side effects that can include diarrhea and uncontrollable
bowel movements.”
Dosage instructions warn that to be effective, Alli must
be taken three times a day. The pills are
projected to cost $1 to $2 per day, with
no insurance coverage since they are over-the-counter medications.
Reed said 120 capsules cost $72.99. There's also the option
of purchasing 60 capsules for $49.99 or 90 for $59.99.
Most notably, health officials argue that the drug's high
cost and limited effectiveness may not be worth its unpleasant
side effects. “The serious side effect of Alli besides
gastrointestinal upset is interference with the body's absorption
of some vitamins. Anyone who takes Alli also should take
a daily multi-vitamin”, said Reed. Customers also
get additional advice.
On the other hand, "The company states that some of
the more unpleasant side effects may be lessened if you
stick to a diet containing 15 grams of fat
or less," said Reed. "If you follow a low-fat
diet along with exercise, chances are you will lose weight
and not need the pill in the first place."
Although Alli may be helpful for a small number with no
history of weight problems, the drug's
advertisements may be misleading for those who don't read
the fine print.